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How the work holds up

What We Do

A family-led nonprofit that uses AI to turn a rare ALS variant into testable science — and puts that work in front of the labs that can prove or disprove it.

From A Single Mutation To A Roadmap

InnerVara starts with one rare, ALS-causing variant and works outward — mapping how it breaks the biology, what might correct it, and which existing science is closest. The result is a structured research map, not a guess.

01
A Rare Variant

One ultra-rare, ALS-causing mutation — the starting point.

02
How It Breaks Biology

Mapping the mechanism — what the mutation actually disrupts.

03
What Could Correct It

Candidate approaches that might restore the broken biology.

04
Tested In Real Labs

Put in front of established labs to prove — or disprove — it.

What We Are — What We're Not

Being clear about our limits is how we stay honest — and useful.

We are
Family-led and independent
AI-driven hypothesis generation
Grounded in published science
Validated by established labs
We're not
A staffed lab or pharma company
A source of medical advice
Claiming to have a cure
A replacement for your doctors
The actual work

Grounded In Evidence And Built To Be Proven Wrong.

Everything we produce is grounded in published science. The research framework is fully citation-verified, and every claim carries an evidence tier — from approved therapy to mechanistic hypothesis — alongside a test that could prove it wrong. Nothing is presented as proven that isn't.

Every claim carries a tier
Approved therapy Clinical evidence Preclinical Mechanistic hypothesis
De-identified molecular figure
Fig. 1 — De-identified molecular figure
Variant attack map
Fig. 2 — Variant attack map (de-identified)

Facing A Rare ALS Diagnosis Yourself?

You don't have to face the maze alone. We've walked it — and we'll help you find your way through.